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Current Issue - March 2019, Volume 13, Issue No. 1

Official Journal of Malaysian Orthopaedic Association and ASEAN Orthopaedic Association

Relative Telomere Length in Blood Leukocytes of Patients with Anterior Cruciate Ligament Injury: A Pilot Study


  1. Cheatham SA, Johnson DL. Current concepts in ACL Injuries. Phys Sportsmed. 2010; 38(3): 61-8.
  2. Smith HC, Vacek P, Johnson RJ, Slauterbeck JR, Hashemi J, Shultz S, et al. Risk factors for anterior cruciate ligament injury: a review of the literature-part 2: hormonal, genetic, cognitive function, previous injury, and extrinsic risk factors. Sports Health. 2012; 4(2): 155-61.
  3. Boden BP, Sheehan FT, Torg JS, Hewett TE. Noncontact anterior cruciate ligament injuries: mechanisms and risk factors. J Am Acad Orthop Surg. 2010; 18(8): 520-7.
  4. Acevedo RJ, Rivera-Vega A, Miranda G, Micheo W. Anterior cruciate ligament injury: identification of risk factors and prevention strategies. Curr Sports Med Rep. 2014; 13(3): 186-91.
  5. Ponsot E, Langberg H, Krogsgaard MR, Kjaer M, Kadi F. Telomere length of anterior crucial ligament after rupture: similar telomere length in injured and noninjured ACL portions. J Orthop Res. 2011; 29(1): 79-83.
  6. Arsenis NC, You T, Ogawa EF, Tinsley GM, Zuo L. Physical activity and telomere length: Impact of aging and potential mechanisms of action. Oncotarget. 2017; 8(27): 45008-19.
  7. Cawthon RM. Telomere measurement by quantitative PCR. Nucleic Acids Res. 2002; 30(10): e47.
  8. Poonpet T, Saetan N, Tanavalee A, Wilairatana V, Yuktanandana P, Honsawek S. Association between leukocyte telomere length and angiogenic cytokines in knee osteoarthritis. Int J Rheum Dis. 2018; 21(1): 118-25.
  9. Dechsupa S, Singhatanadgige W, Limthongkul W, Yingsakmongkol W, Ittipanichpong T, Honsawek S. Alterations of relative telomere length and mitochondrial DNA copy number from ligamentum flavum-derived cells in lumbar spinal stenosis: Pilot study. Chula Med J. 2017; 61(4): 497-509.
  10. Tamayo M, Mosquera A, Rego JI, Fernández-Sueiro JL, Blanco FJ, Fernández JL. Differing patterns of peripheral blood leukocyte telomere length in rheumatologic diseases. Mutat Res. 2010; 683(1-2): 68-73.
  11. Du M, Prescott J, Kraft P, Han J, Giovannucci E, Hankinson SE, et al. Physical activity, sedentary behavior, and leukocyte telomere length in women. Am J Epidemiol. 2012; 175(5): 414-22.
  12. Ludlow AT, Zimmerman JB, Witkowski S, Hearn JW, Hatfield BD, Roth SM. Relationship between physical activity level, telomere length, and telomerase activity. Med Sci Sports Exerc. 2008; 40(10): 1764-71.
  13. Cherkas LF, Hunkin JL, Kato BS, Richards JB, Gardner JP, Surdulescu GL, et al. The association between physical activity in leisure time and leukocyte telomere length. Arch Intern Med. 2008; 168(2): 154-8.
  14. von Zglinicki T. Oxidative stress shortens telomeres. Trends Biochem Sci. 2002; 27(7): 339-44.
  15. Zhu H, Belcher M, van der Harst P. Healthy aging and disease: role for telomere biology. Clin Sci (Lond). 2011; 120(10): 427-40.

Abstract   |   Reference

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About Us

The Malaysian Orthopaedic Journal is a peer-reviewed journal that is published three times a year in both print and electronic online version. The purpose of this journal is to publish original research studies, evaluation of current practices and case reports in various subspecialties of orthopaedics and traumatology, as well as associated fields like basic science, biomedical engineering, rehabilitation medicine and nursing.

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